Integration of Mature Adipocytes to Build-Up a Functional Three-Layered Full-Skin Equivalent
نویسندگان
چکیده
منابع مشابه
Integration of Mature Adipocytes to Build-Up a Functional Three-Layered Full-Skin Equivalent
Large, deep full-thickness skin wounds from high-graded burns or trauma are not able to reepithelialize sufficiently, resulting in scar formation, mobility limitations, and cosmetic deformities. In this study, in vitro-constructed tissue replacements are needed. Furthermore, such full-skin equivalents would be helpful as in vivo-like test systems for toxicity, cosmetic, and pharmaceutical testi...
متن کاملGeneration of a three-dimensional full thickness skin equivalent and automated wounding.
In vitro models are a cost effective and ethical alternative to study cutaneous wound healing processes. Moreover, by using human cells, these models reflect the human wound situation better than animal models. Although two-dimensional models are widely used to investigate processes such as cellular migration and proliferation, models that are more complex are required to gain a deeper knowledg...
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A variety of skin substitutes that restore epidermal and dermal structures are currently available on the market. However, the main focus in research and clinical application lies on dermal and epidermal substitutes whereas the development of a subcutaneous replacement (hypodermis) is often disregarded. In this study we used fibrin sealant as hydrogel scaffold to generate a three-layered skin s...
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Background and Aim: Restoration of endodontically treated teeth is one of the most important and challenging topics in restorative dentistry. Longevity of such restorations is an essential factor in treatment planning. Amalgam build-up is a conservative method for restoration of endodontically treated teeth. Therefore, this study aimed to assess the longevity of this type of restoration in endo...
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Several techniques exist to select and materialize a proper set of data in a suitable structure that manage the queries submitted to the online analytical processing systems. These techniques are called view management techniques, which consist of three research areas: 1) view selection to materialize, 2) query processing and rewriting using the materialized views, and 3) maintaining materializ...
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ژورنال
عنوان ژورنال: Tissue Engineering Part C: Methods
سال: 2016
ISSN: 1937-3384,1937-3392
DOI: 10.1089/ten.tec.2016.0141